cpemberton's blog

05/13/2015 New paper accepted for publication in JASA-EL

A new paper, "Direct visualization of shear waves in micellar fluid using microspheres", authored by Cecille Labuda. Connor Tierney, Sunethra Dayavansha and Joseph Gladden has been accepted for publication in the Journal of the Acoustical Society Express Letters.  The paper will soon be available online and will be inthe next print volume of the journal.

05/07/2015 Davis Rogers and Connor Tierney inducted into Sigma Pi Sigma.

Two of our undergrads, Davis Rogers and Connor Tierney, were inducted into Sigma Pi Sigma, the Physics honor society.  Four other students were also inducted.  Students are only inducted into the honor society by invitation and only students with top academic performances who perform research or outreach in physics are invited to join.

The 2015 Sigma Pi Sigma inductees were (from left to right), Ryan Chapman, Davis Rogers, Emily Smith, Connor Tierney and Piero Bracamonte.

20150423-27: Connor Tierney, Davis Rogers and Taylor Miller defend honors theses.

Connor Tierney, Davis Rogers and Taylor Miller successfully defended their honors theses on 04/23/2015.  Connor's thesis was titled "Direct Visualization of Shear Waves Using Microspheres."  Davis's thesis was titled "Comparison of the Spatial Distributions of Cavitation Damage with the Measured Diffraction Patterns for a High-Power Ultrasonic Transducer."  Taylor's thesis was titled "An Assessment of the Angular Spectrum Method for the Propagation of Ultrasound."  Click here for photo gallery.

20150414 Jason Raymond gives colloquium talk in the Physics department.

Jason Raymond, who was a member of the Ultrasonics group from 2002-2009, returned to give a colloquium talk on his work on echogenic liposomes.  Jason is currently finishing up a stint at the University of Cincinnati where he got his PhD in Biomedical Engineering.

Abstract

Lipid-shelled Ultrasound Contrast Agents for Imaging and Therapy: Stable and Unstable Dynamics

Lipid-shelled ultrasound contrast agents known as “echogenic liposomes” are nanoparticle theragnostic agents being developed to target and treat cardiovascular disease. This talk will present recent results using an ultra-high-speed optical imaging approach to investigate the acoustic response of these agents. The investigations utilize an ultra high-speed imaging system (“Brandaris 128”, Rotterdam, the Netherlands) which was developed for imaging physical phenomena such as ultrasound-microbubble interaction at up to 20 million frames per second. Results of two studies using this unique imaging facility will be presented. In the first study, we demonstrate a method to estimate the acousto-mechanical properties based on the impulse response. In the second study, we investigate the response to multiple-cycle acoustic pulses, which result in loss of gas from individual particles. These studies demonstrate that acoustically-active or “echogenic” liposomes can be considered a theragnostic agent, with both stable and unstable dynamics that can be exploited using different ultrasound parameter regimes.

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